Intro -- Contents -- Preface -- Chapter 1 The histamine H4 receptor story -- Chapter 2 Histamine H4 Receptor Ligands -- Chapter 3 Histamine metabolism -- Chapter 4 Histamine Receptors and Inflammatory Cells -- Chapter 5 Histamine in Asthmatic and Fibrotic Lung Disorders -- Chapter 6 Histamine in Atopic Disorders: Atopic Dermatitis and Pruritus -- Chapter 7 Non-professional Histamine Producing Cells, Immune Responses and Autoimmunity -- Chapter 8 Histamine in Cancer -- Chapter 9 Non Receptor-mediated Histamine Actions -- Chapter 10 Perspectives in H4R Research and Therapeutic Exploitation -- References -- List of Figures -- List of Tables -- Index.

The histamine H4 receptor is the most recently detected histamine receptor subtype. The molecular signaling mechanism, function & localization of the receptor will be described together with its influence on physiological and pathophysiological properties. Possibilities of novel therapeutic inventions with newly designed compounds will be included as well as numerous biochemical and pharmacological in vitro & in vivo models on different species.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2022. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.