Intro -- Preface -- Contents -- 1 Epidemiology -- Abstract -- 1.1 Tuberculosis in History -- 1.2 Pathogen -- 1.3 Epidemiology -- 1.4 Prognosis -- 2 Pathogenesis -- Abstract -- 2.1 Transmission -- 2.2 The Innate Immune Response -- 2.3 The Adaptive Immune Reponse -- 2.4 The Complex Role of TNF and Its Genetic Control -- 2.5 The Tuberculoma -- 2.6 Vitamin D and the Immune Response -- 2.6.1 Vitamin D Metabolism -- 2.6.2 Antimicrobial Effects of Vitamin D -- 2.6.3 Vitamin D Deficiency and Susceptibility to Tuberculosis -- 3 Clinical Manifestations -- Abstract -- 3.1 Primary Tuberculosis -- 3.2 Pulmonary Tuberculosis -- 3.2.1 Parenchymal Disease -- 3.2.2 Endobronchial Tuberculosis -- 3.2.3 Intra-Thoracic Lymphnode Disease -- 3.3 Extra-Pulmonary Tuberculosis -- 3.3.1 Pleural Tuberculosis -- 3.3.2 Miliary Tuberculosis -- 3.3.3 Extra-Thoracic Lymphnode Disease -- 3.3.4 Central Nervous System Tuberculosis -- 3.3.5 Tuberculous Pericarditis -- 3.3.6 Spinal Tuberculosis -- 3.3.7 Other Forms of Extra-Pulmonary Tuberculosis -- 4 Diagnosis -- Abstract -- 4.1 Smear Microscopy -- 4.2 Mycobacterial Culture -- 4.3 Nucleic Acid Amplification Tests -- 4.4 Diagnosing Drug-Resistant Tuberculosis -- 4.5 Other Diagnostic Methods -- 4.6 Diagnosing Latent Tuberculosis Infection -- 5 Treatment -- Abstract -- 5.1 First-Line Antituberculous Treatment -- 5.2 HIV Associated Tuberculosis -- 5.3 Treatment of Drug-Resistant Tuberculosis -- 5.4 The Role of Fluoroquinolones -- 5.5 Bedaquiline -- 5.6 Delamanid -- 6 Prevention -- Abstract -- 6.1 Prophylactic Treatment -- 6.2 Prophylactic Treatment in Multi-drug Resistant Tuberculosis -- 6.3 Vaccines -- 6.4 Concluding Remarks -- References -- Index.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2022. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.